Lysophosphatidylcholine Acyltransferase 2 (LPCAT2)
AYTL1; Acyltransferase Like 1; 1-acylglycerol-3-phosphate O-acyltransferase 11; Lysophosphatidic acid acyltransferase alpha; 1-alkylglycerophosphocholine O-acetyltransferase
LPCAT2 encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine.
The protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The deduced full-length protein contains an N-terminal catalytic domain and 2 cation-binding EF-hand motifs in its C-terminal region.Epitope-tagged Lpcat2 was expressed mainly in the ER and Golgi of transfected Chinese hamster ovary cells.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Hu01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Hu01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Hu01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Hu01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Hu01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Mu01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Mu01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Mu01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Mu01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Mu01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Ra01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Ra01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Ra01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Ra01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Ra01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Ca01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Ca01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Ca01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Ca01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Ca01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Po01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Po01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Po01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Po01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Po01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Bo01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Bo01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Bo01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Bo01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Bo01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Rb01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Rb01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Rb01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Rb01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Rb01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ275Mo01 | Recombinant Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ275Mo01 | Monoclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IP. |
| PAQ275Mo01 | Polyclonal Antibody to Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ275Mo01 | CLIA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | CLIA assay for Antigen Detection |
| ELQ275Mo01 | ELISA Kit for Lysophosphatidylcholine Acyltransferase 2 (LPCAT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:lyso-PAF acetyltransferase."
J. Biol. Chem. 282:6532-6539(2007) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Enzymatic activity of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 11: upregulated in breast and cervical cancers."
J. Lipid Res. 51:2143-2152(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine."
J. Biol. Chem. 286:21330-21339(2011) [PubMed] [Europe PMC] [Abstract]