G Protein Coupled Receptor 109B (GPR109B)
HCAR3; NIACR2; HM74; HCA3; HM74B; PUMAG; Puma-g; Niacin Receptor 2; Nicotinic acid receptor 2; Hydroxycarboxylic acid receptor 3
Chemokine receptors are members of the 7-transmembrane, G protein-coupled receptor (GPCR) family that recognize small proteins responsible for the directed migration of specific cell types.
Sequence analysis predicted that the 387-amino acid, GPCR-type protein has significant homology to the B2 bradykinin receptor (BDKRB2) and to the thrombin receptor (F2R). Northern blot analysis revealed expression of a 2.3-kb HM74 transcript in peripheral blood mononuclear cells and neutrophils.The HM74 protein is a potential 7 transmembrane-spanning receptor that shares 96% identity with HM74A (GPR109A). HM74 expression in spleen, followed by lymphocytes and adipose tissue. Heart, placenta, prostate, and bone marrow showed lower expression, and little to no expression was detected in all other tissues examined.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Hu01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Hu01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Hu01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Hu01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Hu01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Mu01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Mu01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Mu01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Mu01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Mu01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Ra01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Ra01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Ra01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Ra01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Ra01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Ca01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Ca01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Ca01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Ca01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Ca01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Po01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Po01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Po01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Po01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Po01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Bo01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Bo01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Bo01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Bo01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Bo01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Rb01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Rb01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Rb01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Rb01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Rb01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPQ048Mo01 | Recombinant G Protein Coupled Receptor 109B (GPR109B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAQ048Mo01 | Monoclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IP. |
| PAQ048Mo01 | Polyclonal Antibody to G Protein Coupled Receptor 109B (GPR109B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLQ048Mo01 | CLIA Kit for G Protein Coupled Receptor 109B (GPR109B) | CLIA assay for Antigen Detection |
| ELQ048Mo01 | ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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J. Biol. Chem. 284:21928-21933(2009) [PubMed] [Europe PMC] [Abstract]
"International union of basic and clinical pharmacology. LXXXII: nomenclature and classification of hydroxy-carboxylic acid receptors (GPR81, GPR109A, and GPR109B)."
Pharmacol. Rev. 63:269-290(2011) [PubMed] [Europe PMC] [Abstract]