Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka)
PIK4CA; PI4K-ALPHA; pi4K230
PI4Ka catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. Two transcript variants encoding different isoforms have been described for this gene.The predicted 854-amino acid protein has a calculated molecular mass of 97 kD. It contains an ankyrin repeat, a lipid kinase unique domain, a pleckstrin-homology domain, and a lipid kinase catalytic domain. PI4K-alpha has high amino acid sequence similarity to the yeast PI 4-kinases STT4 and PIK1; it has less amino acid sequence similarity to the catalytic domains of mammalian and yeast PI 3-kinases and to the yeast TOR family of proteins.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Hu01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Hu01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Hu01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Hu01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Hu01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Mu01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Mu01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Mu01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Mu01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Mu01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Ra01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Ra01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Ra01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Ra01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Ra01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Ca01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Ca01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Ca01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Ca01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Ca01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Po01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Po01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Po01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Po01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Po01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Bo01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Bo01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Bo01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Bo01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Bo01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Rb01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Rb01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Rb01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Rb01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Rb01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP906Mo01 | Recombinant Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP906Mo01 | Monoclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IP. |
| PAP906Mo01 | Polyclonal Antibody to Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP906Mo01 | CLIA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | CLIA assay for Antigen Detection |
| ELP906Mo01 | ELISA Kit for Phosphatidylinositol-4-Kinase Catalytic Alpha (PI4Ka) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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J. Biol. Chem. 269:28878-28884(1994) [PubMed] [Europe PMC] [Abstract]
"Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230."
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
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J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]