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Meprin A Alpha (MEP1a)

PPHA; PABA Peptide Hydrolase; Endopeptidase-2; N-benzoyl-L-tyrosyl-P-amino-Benzoic Acid Hydrolase Subunit Alpha; PABA Peptide Hydrolase

SPN P899
HGNC 7015
MGI 96963
PubMed 10898933
RGD 3080
UniProt Q16819
Wiki MEP1A
Meprins, members of the 'astacin family' of metalloendopeptidases, are capable of hydrolyzing a variety of peptide and protein substrates. Two forms of meprins, designated A and B. Meprin A (EC 3.4.24.18) is the best characterized of the meprins and is known to hydrolyze peptides such as bradykinin, melanocyte-stimulating hormone, neurotensin, luteinizing hormone releasing hormone, transforming growth factor-alpha, and parathyroid hormone. Meprin B from mouse kidney has latent proteolytic activity against polypeptide substrates. Rat meprin A is sometimes referred to as endopeptidase-2 or endopeptidase-24.18; human meprin A is also called N-benzoyl-L-tyrosyl-p-aminobenzoic acid (PABA peptide) hydrolase (PPH).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Hu01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Hu01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Hu01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Hu01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Hu01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Mu01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Mu01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Mu01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Mu01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Mu01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Ra01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Ra01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Ra01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Ra01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Ra01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Ca01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Ca01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Ca01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Ca01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Ca01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Po01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Po01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Po01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Po01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Po01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Bo01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Bo01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Bo01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Bo01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Bo01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Rb01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Rb01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Rb01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Rb01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Rb01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP899Mo01 Recombinant Meprin A Alpha (MEP1a) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP899Mo01 Monoclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IP.
PAP899Mo01 Polyclonal Antibody to Meprin A Alpha (MEP1a) WB; IHC; ICC; IF.
Assay Kits CLP899Mo01 CLIA Kit for Meprin A Alpha (MEP1a) CLIA assay for Antigen Detection
ELP899Mo01 ELISA Kit for Meprin A Alpha (MEP1a) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells."
FEBS Lett. 335:367-375(1993) [PubMed] [Europe PMC] [Abstract]

"Human and mouse homo-oligomeric meprin A metalloendopeptidase: substrate and inhibitor specificities."
Biol. Chem. 388:1163-1172(2007) [PubMed] [Europe PMC] [Abstract]

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