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Vasohibin 1 (VASH1)

Vasohibin protein contains a cluster of basic amino acids in its C terminus and no classic secretion signal sequence. Vasohibin expression was robust between embryonic weeks 6 to 12 in heart, brain, kidney, lung, skeletal muscle, and whole embryo. Immunohistochemical analysis detected vasohibin at the endothelial layer of placenta and brain.
The deduced protein contains 365 amino acids. RT-PCR ELISA detected intermediate expression in adult heart, brain, lung, liver, kidney, ovary, and spinal cord, as well as in fetal brain. Lower expression was detected in skeletal muscle, testis, pancreas, and fetal liver, and little to no expression was detected in spleen. All specific adult brain regions examined showed low to moderate expression.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Hu01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Hu01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Hu01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Hu01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Hu01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Mu01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Mu01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Mu01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Mu01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Mu01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Ra01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Ra01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Ra01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Ra01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Ra01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Ca01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Ca01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Ca01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Ca01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Ca01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Po01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Po01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Po01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Po01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Po01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Bo01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Bo01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Bo01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Bo01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Bo01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Rb01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Rb01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Rb01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Rb01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Rb01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP842Mo01 Recombinant Vasohibin 1 (VASH1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAP842Mo01 Monoclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IP.
PAP842Mo01 Polyclonal Antibody to Vasohibin 1 (VASH1) WB; IHC; ICC; IF.
Assay Kits CLP842Mo01 CLIA Kit for Vasohibin 1 (VASH1) CLIA assay for Antigen Detection
ELP842Mo01 ELISA Kit for Vasohibin 1 (VASH1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
DNA Res. 6:197-205(1999) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 14."
Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Vasohibin as an endothelium-derived negative feedback regulator of angiogenesis."
J. Clin. Invest. 114:898-907(2004) [PubMed] [Europe PMC] [Abstract]

"Gene regulation of a novel angiogenesis inhibitor, vasohibin, in endothelial cells."
Biochem. Biophys. Res. Commun. 327:700-706(2005) [PubMed] [Europe PMC] [Abstract]

"Multiple processing forms and their biological activities of a novel angiogenesis inhibitor vasohibin."
Biochem. Biophys. Res. Commun. 342:640-646(2006) [PubMed] [Europe PMC] [Abstract]

"Vasohibin prevents arterial neointimal formation through angiogenesis inhibition."
Biochem. Biophys. Res. Commun. 345:919-925(2006) [PubMed] [Europe PMC] [Abstract]