UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7)
UGTB2B9; UDPGTh-2; 3,4-catechol estrogen-specific UDPGT
UGT2B7 is a phase II metabolism isoenzyme found to be active in the liver, kidneys, epithelial cells of the lower gastrointestinal tract and also has been reported in the brain. UGT2B7 is capable of glucosidation of hyodesoxycholic acid in the liver, but unlike the 2B4 isoform, 2B7 is also able to glucuronidate various steroid hormones and fatty acids. It is also able to conjugate major classes of drugs such as analgesics (morphine), carboxylic nonsteroidal anti-inflammatory drugs (ketoprofen) and anticarcinogens. UGT2B7 is the major enzyme isoform for the metabolism of morphine to the main metabolites, morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G), and consequently altered UGT2B7 activity can significantly affect both the effectiveness and side effects of morphine, as well as some related opiate drugs.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Hu01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Hu01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Hu01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Hu01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Hu01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Mu01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Mu01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Mu01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Mu01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Mu01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Ra01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Ra01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Ra01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Ra01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Ra01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Ca01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Ca01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Ca01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Ca01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Ca01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Po01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Po01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Po01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Po01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Po01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Bo01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Bo01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Bo01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Bo01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Bo01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Rb01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Rb01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Rb01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Rb01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Rb01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP814Mo01 | Recombinant UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP814Mo01 | Monoclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IP. |
| PAP814Mo01 | Polyclonal Antibody to UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP814Mo01 | CLIA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | CLIA assay for Antigen Detection |
| ELP814Mo01 | ELISA Kit for UDP Glucuronosyltransferase 2 Family, Polypeptide B7 (UGT2B7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7."
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