Semenogelin II (SEMG2)
SGII
SEMG2 is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20.
The transcription units are composed of 3 exons, of which the first encodes the signal peptide, the second encodes secreted protein, and the third contains solely 3-prime, noncoding nucleotides. The nucleotide sequences exhibited a similarity of close to 90% in the exons and greater than 80% in the introns and flanking nucleotides.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Hu01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Hu01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Hu01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Hu01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Hu01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Mu01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Mu01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Mu01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Mu01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Mu01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Ra01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Ra01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Ra01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Ra01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Ra01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Ca01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Ca01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Ca01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Ca01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Ca01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Po01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Po01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Po01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Po01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Po01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Bo01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Bo01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Bo01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Bo01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Bo01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Rb01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Rb01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Rb01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Rb01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Rb01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPP558Mo01 | Recombinant Semenogelin II (SEMG2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAP558Mo01 | Monoclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IP. |
| PAP558Mo01 | Polyclonal Antibody to Semenogelin II (SEMG2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLP558Mo01 | CLIA Kit for Semenogelin II (SEMG2) | CLIA assay for Antigen Detection |
| ELP558Mo01 | ELISA Kit for Semenogelin II (SEMG2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning of epididymal and seminal vesicular transcripts encoding a semenogelin-related protein."
Proc. Natl. Acad. Sci. U.S.A. 89:4559-4563(1992) [PubMed] [Europe PMC] [Abstract]
"Gene structure of semenogelin I and II. The predominant proteins in human semen are encoded by two homologous genes on chromosome 20."
J. Biol. Chem. 267:18080-18084(1992) [PubMed] [Europe PMC] [Abstract]
"Evolution of the hominoid semenogelin genes, the major proteins of ejaculated semen."
J. Mol. Evol. 57:261-270(2003) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and comparative analysis of human chromosome 20."
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
"Isolation and structure determination of two peptides occurring in human seminal plasma."
Biol. Chem. Hoppe-Seyler 370:353-356(1989) [PubMed] [Europe PMC] [Abstract]
"Isolation and characterization of the major gel proteins in human semen, semenogelin I and semenogelin II."
Eur. J. Biochem. 238:48-53(1996) [PubMed] [Europe PMC] [Abstract]
"Characterization of semenogelin II and its molecular interaction with prostate-specific antigen and protein C inhibitor."
Eur. J. Biochem. 238:88-96(1996) [PubMed] [Europe PMC] [Abstract]