Hydrogen Voltage Gated Channel Protein 1 (HVCN1)
Hv1; VSOP; Voltage Sensor Domain-Only Protein; Hydrogen voltage-gated channel 1
HVCN1 is a voltage-gated proton channel highly expressed in immune tissues. Channels like HVCN1 mediate the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. High expression in spleen, whole blood, bone marrow, and macrophages, with weak expression in all other tissues examined.
The deduced 273-amino acid protein contains 4 transmembrane segments that correspond to the voltage-sensing domain of other ion channels, but it lacks transmembrane segments characteristic of a pore domain. Database analysis showed enrichment of HV1 in immune tissues, such as lymph node, B lymphocytes, monocytes, and spleen. RNA dot blot analysis detected highest expression in lymph node. Western blot analysis revealed a 32-kD HV1 protein in most immune tissue examined.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Hu01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Hu01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Hu01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Hu01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Hu01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Mu01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Mu01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Mu01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Mu01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Mu01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Ra01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Ra01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Ra01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Ra01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Ra01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Ca01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Ca01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Ca01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Ca01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Ca01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Po01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Po01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Po01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Po01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Po01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Bo01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Bo01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Bo01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Bo01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Bo01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Rb01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Rb01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Rb01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Rb01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Rb01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO905Mo01 | Recombinant Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO905Mo01 | Monoclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IP. |
| PAO905Mo01 | Polyclonal Antibody to Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO905Mo01 | CLIA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | CLIA assay for Antigen Detection |
| ELO905Mo01 | ELISA Kit for Hydrogen Voltage Gated Channel Protein 1 (HVCN1) | Enzyme-linked immunosorbent assay for Antigen Detection |
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