Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1)
HS6ST
HS6ST1 is a member of the heparan sulfate biosynthetic enzyme family. Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biological activities. This enzyme is a type II integral membrane protein and is responsible for 6-O-sulfation of heparan sulfate. This enzyme does not share significant sequence similarity with other known sulfotransferases.
The predicted 401-amino acid human HS6ST protein is a type II transmembrane protein, with an N-terminal transmembrane domain. A putative cleavage site occurs near the C-terminal end of the transmembrane domain.HS6ST contains 2 potential N-glycosylation sites.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Hu01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Hu01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Hu01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Hu01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Hu01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Mu01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Mu01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Mu01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Mu01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Mu01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Ra01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Ra01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Ra01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Ra01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Ra01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Ca01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Ca01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Ca01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Ca01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Ca01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Po01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Po01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Po01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Po01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Po01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Bo01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Bo01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Bo01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Bo01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Bo01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Rb01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Rb01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Rb01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Rb01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Rb01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO870Mo01 | Recombinant Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO870Mo01 | Monoclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IP. |
| PAO870Mo01 | Polyclonal Antibody to Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO870Mo01 | CLIA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | CLIA assay for Antigen Detection |
| ELO870Mo01 | ELISA Kit for Heparan Sulfate-6-O-Sulfotransferase 1 (HS6ST1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular characterization and expression of heparan-sulfate 6-sulfotransferase."
J. Biol. Chem. 273:9208-9213(1998) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism."
Proc. Natl. Acad. Sci. U.S.A. 108:11524-11529(2011) [PubMed] [Europe PMC] [Abstract]
"The prevalence of CHD7 missense versus truncating mutations is higher in patients with Kallmann syndrome than in typical CHARGE patients."
J. Clin. Endocrinol. Metab. 99:E2138-2143(2014) [PubMed] [Europe PMC] [Abstract]