Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM)
GPAT1
Glycerol-3-phosphate acyltransferase (GPAT; EC 2.3.1.15), which catalyzes the initial and committing step in glycerolipid biosynthesis, is predicted to play a pivotal role in the regulation of cellular triacylglycerol and phospholipid levels. Two mammalian forms of GPAT have been identified on the basis of localization to either the endoplasmic reticulum or mitochondria.
Mitochondrial Gpat, or Gpam, is highly expressed in mouse lipogenic tissues, such as liver and adipose tissue. In animal studies, fasting/refeeding and administration of insulin caused a dramatic induction of Gpat. Consistent with these observations, putative carbohydrate-responsive sequences were identified in the proximal promoter of the murine cDNA.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Hu01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Hu01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Hu01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Hu01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Hu01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Mu01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Mu01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Mu01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Mu01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Mu01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Ra01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Ra01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Ra01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Ra01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Ra01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Ca01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Ca01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Ca01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Ca01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Ca01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Po01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Po01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Po01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Po01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Po01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Bo01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Bo01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Bo01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Bo01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Bo01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Rb01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Rb01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Rb01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Rb01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Rb01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO772Mo01 | Recombinant Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO772Mo01 | Monoclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IP. |
| PAO772Mo01 | Polyclonal Antibody to Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO772Mo01 | CLIA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | CLIA assay for Antigen Detection |
| ELO772Mo01 | ELISA Kit for Glycerol-3-Phosphate Acyltransferase, Mitochondrial (GPAM) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
"Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
DNA Res. 7:273-281(2000) [PubMed] [Europe PMC] [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
"AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase."
J. Biol. Chem. 283:10048-10057(2008) [PubMed] [Europe PMC] [Abstract]
"Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
Proteomics 8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]