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Glycoprotein A33 (GPA33)

Cell surface A33 antigen

GPA33 is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Hu01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Hu01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Hu01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Hu01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Hu01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Mu01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Mu01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Mu01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Mu01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Mu01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Ra01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Ra01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Ra01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Ra01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Ra01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Ca01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Ca01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Ca01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Ca01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Ca01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Po01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Po01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Po01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Po01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Po01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Bo01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Bo01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Bo01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Bo01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Bo01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Rb01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Rb01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Rb01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Rb01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Rb01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPO771Mo01 Recombinant Glycoprotein A33 (GPA33) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAO771Mo01 Monoclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IP.
PAO771Mo01 Polyclonal Antibody to Glycoprotein A33 (GPA33) WB; IHC; ICC; IF.
Assay Kits CLO771Mo01 CLIA Kit for Glycoprotein A33 (GPA33) CLIA assay for Antigen Detection
ELO771Mo01 ELISA Kit for Glycoprotein A33 (GPA33) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily."
Proc. Natl. Acad. Sci. U.S.A. 94:469-474(1997) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Characterization of posttranslational modifications of human A33 antigen, a novel palmitoylated surface glycoprotein of human gastrointestinal epithelium."
Biochem. Biophys. Res. Commun. 236:682-686(1997) [PubMed] [Europe PMC] [Abstract]