Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2)
SD; B4GALGT2; B4GALT; Cad; GALGT2; Sda; Sd(a) beta-1,4-GalNAc transferase; UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase
B4GALNT2 catalyzes the last step in the biosynthesis of the human Sd(a) antigen through the addition of an N-acetylgalactosamine residue via a beta-1,4 linkage to a subterminal galactose residue substituted with an alpha-2,3-linked sialic acid. B4GALNT2 also catalyzes the last step in the biosynthesis of the Cad antigen. The longer transcript encodes a deduced 566-amino acid protein with a calculated molecular mass of 63.3 kD. It contains an N-terminal cytosolic domain, followed by a transmembrane domain and a long catalytic domain. The shorter transcript encodes a deduced 506-amino acid protein with calculated molecular mass of 57.0 kD. It has a different N-terminal cytosolic domain than the full-length form. Northern blot analysis detected B4GALNT2 transcripts of 8.8, 6.1, 4.7, 3.8, and 1.65 kb.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Hu01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Hu01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Hu01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Hu01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Hu01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Mu01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Mu01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Mu01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Mu01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Mu01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Ra01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Ra01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Ra01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Ra01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Ra01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Ca01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Ca01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Ca01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Ca01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Ca01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Po01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Po01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Po01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Po01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Po01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Bo01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Bo01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Bo01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Bo01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Bo01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Rb01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Rb01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Rb01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Rb01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Rb01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPO187Mo01 | Recombinant Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAO187Mo01 | Monoclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IP. |
| PAO187Mo01 | Polyclonal Antibody to Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | WB; IHC; ICC; IF. | |
| Assay Kits | CLO187Mo01 | CLIA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | CLIA assay for Antigen Detection |
| ELO187Mo01 | ELISA Kit for Beta-1,4-N-Acetyl Galactosaminyl Transferase 2 (b4GALNT2) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain."
Biochem. J. 373:369-379(2003) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning of the human beta1,4 N-acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain."
J. Biochem. 134:675-682(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
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