Histone Cluster 1, H1a (HIST1H1A)
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.
HIST1H1a is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Hu01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Hu01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Hu01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Hu01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Hu01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Mu01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Mu01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Mu01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Mu01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Mu01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Ra01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Ra01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Ra01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Ra01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Ra01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Ca01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Ca01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Ca01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Ca01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Ca01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Po01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Po01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Po01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Po01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Po01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Bo01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Bo01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Bo01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Bo01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Bo01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Rb01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Rb01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Rb01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Rb01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Rb01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN983Mo01 | Recombinant Histone Cluster 1, H1a (HIST1H1A) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN983Mo01 | Monoclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IP. |
| PAN983Mo01 | Polyclonal Antibody to Histone Cluster 1, H1a (HIST1H1A) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN983Mo01 | CLIA Kit for Histone Cluster 1, H1a (HIST1H1A) | CLIA assay for Antigen Detection |
| ELN983Mo01 | ELISA Kit for Histone Cluster 1, H1a (HIST1H1A) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Human H1 histones: conserved and varied sequence elements in two H1 subtype genes."
Eur. J. Cell Biol. 49:110-115(1989) [PubMed] [Europe PMC] [Abstract]
"The human and mouse replication-dependent histone genes."
Genomics 80:487-498(2002) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"A proposal for a coherent mammalian histone H1 nomenclature correlated with amino acid sequences."
Protein Sci. 3:575-587(1994) [PubMed] [Europe PMC] [Abstract]
"The C-terminal domain is the primary determinant of histone H1 binding to chromatin in vivo."
J. Biol. Chem. 279:20028-20034(2004) [PubMed] [Europe PMC] [Abstract]
"H1 family histones in the nucleus. Control of binding and localization by the C-terminal domain."
J. Biol. Chem. 280:27809-27814(2005) [PubMed] [Europe PMC] [Abstract]
"Histone H1 subtype preferences of DFF40 and possible nuclear localization of DFF40/45 in normal and trichostatin A-treated NB4 leukemic cells."
Apoptosis 15:128-138(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]