SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)

BAF155; SRG3; Rsc8; CRACC1; SWI/SNF complex 155 kDa subunit; BRG1-associated factor 155; SWI/SNF complex subunit SMARCC1

SPN	N462
HGNC	11104
MGI	1203524
PubMed	24434203
RGD	1304850
UniProt	Q92922
Wiki	SMARCC1

The SMARCC1 gene encodes BAF155, the 155-kD subunit of the SWI/SNF chromatin remodeling complex. Chromatin is actively remodeled during development. Chromatin remodeling of certain genes appears to precede their transcriptional activation. In yeast, the multisubunit SWI/SNF complex is thought to be responsible for chromatin remodeling.This gene encodes a polypeptide of 1,104 amino acids, and is homologous both to the yeast SWI3 gene and to BAF170, another of the proteins in this chromatin remodeling complex. SWI3, BAF155, and BAF170 all contain a predicted leucine zipper region (a dimerization motif for a variety of transcription factors) and a myb-like tryptophan-repeat domain. Western blot analysis and EST database analysis revealed that BAF155 is expressed in many tissues.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Hu01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Hu01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Hu01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Hu01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Hu01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Mu01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Mu01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Mu01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Mu01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Mu01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Ra01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Ra01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Ra01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Ra01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Ra01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Ca01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Ca01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Ca01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Ca01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Ca01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Po01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Po01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Po01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Po01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Po01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Bo01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Bo01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Bo01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Bo01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Bo01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Rb01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Rb01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Rb01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Rb01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Rb01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPN462Mo01	Recombinant SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAN462Mo01	Monoclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IP.
Antibodies	PAN462Mo01	Polyclonal Antibody to SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	WB; IHC; ICC; IF.
Assay Kits	CLN462Mo01	CLIA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	CLIA assay for Antigen Detection
Assay Kits	ELN462Mo01	ELISA Kit for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily C, Member 1 (SMARCC1)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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, Submitted (JUL-2007) to UniProtKB

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"Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits."
Mol. Cell 3:247-253(1999) [PubMed] [Europe PMC] [Abstract]

"Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest."
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"Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes."
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"BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation."
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"Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex."
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"Ubiquitin-dependent and ubiquitin-independent control of subunit stoichiometry in the SWI/SNF complex."
J. Biol. Chem. 285:35665-35674(2010) [PubMed] [Europe PMC] [Abstract]

"Solution structure of the SANT domain of human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1."
Submitted (APR-2008) to the PDB data bank