C-Type Lectin Domain Family 3, Member B (CLEC3B)
TN; TNA; Tetranectin; Plasminogen Binding Protein; Plasminogen kringle 4-binding protein
Tetranectin, a tetrameric protein isolated from human plasma, has 4 identical and noncovalently bound polypeptide chains, each of 181 amino acid residues. It has a specific binding affinity for sulfated polysaccharides and the kringle 4 of plasminogen. The plasma concentration of tetranectin is reduced in patients with various malignancies. The gene is about 12 kb and contains 2 intervening sequences. It encodes a 202-residue pretetranectin, with a signal peptide of 21 amino acid residues followed by the tetranectin sequence of 181 amino acid residues. Northern blot analysis demonstrated tetranectin mRNA in all 8 tissues tested, with the highest concentration in lung. Southern blot analysis demonstrated hybridization to 2 genes, but it was not determined whether these were allelic or nonallelic.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Hu01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Hu01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Hu01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Hu01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Hu01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Mu01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Mu01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Mu01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Mu01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Mu01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Ra01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Ra01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Ra01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Ra01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Ra01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Ca01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Ca01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Ca01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Ca01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Ca01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Po01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Po01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Po01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Po01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Po01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Bo01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Bo01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Bo01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Bo01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Bo01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Rb01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Rb01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Rb01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Rb01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Rb01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPN038Mo01 | Recombinant C-Type Lectin Domain Family 3, Member B (CLEC3B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAN038Mo01 | Monoclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IP. |
| PAN038Mo01 | Polyclonal Antibody to C-Type Lectin Domain Family 3, Member B (CLEC3B) | WB; IHC; ICC; IF. | |
| Assay Kits | CLN038Mo01 | CLIA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | CLIA assay for Antigen Detection |
| ELN038Mo01 | ELISA Kit for C-Type Lectin Domain Family 3, Member B (CLEC3B) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Tetranectin, a plasminogen kringle 4-binding protein. Cloning and gene expression pattern in human colon cancer."
Lab. Invest. 67:253-262(1992) [PubMed] [Europe PMC] [Abstract]
"The gene structure of tetranectin, a plasminogen binding protein."
FEBS Lett. 309:15-19(1992) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence, annotation and analysis of human chromosome 3."
Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Primary structure of tetranectin, a plasminogen kringle 4 binding plasma protein: homology with asialoglycoprotein receptors and cartilage proteoglycan core protein."
Biochemistry 26:6757-6764(1987) [PubMed] [Europe PMC] [Abstract]
"Mass spectrometric characterisation of post-translational modification and genetic variation in human tetranectin."
Biol. Chem. 380:1307-1314(1999) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Crystal structure of tetranectin, a trimeric plasminogen-binding protein with an alpha-helical coiled coil."
FEBS Lett. 412:388-396(1997) [PubMed] [Europe PMC] [Abstract]
"Structure of the C-type lectin carbohydrate recognition domain of human tetranectin."
Acta Crystallogr. D 54:757-766(1998) [PubMed] [Europe PMC] [Abstract]