EGF Like Domain Protein, Multiple 7 (EGFL7)
ZNEU1; MEGF7; Zneu1; Vascular endothelial statin; EGF Like Domain Containing 7; Epidermal growth factor-like protein 7; Multiple epidermal growth factor-like domains protein 7
The deduced 275-amino acid protein has a calculated molecular mass of 29.8 kD. The mouse and human EGFL7 proteins both contain an N-terminal cleavable signal peptide followed by 2 epidermal growth factor (EGF)-like domains, and they share 78% amino acid identity. Northern blot analysis detected a transcript of about 1.6 kb only in mouse heart, lung, and kidney. In situ hybridization showed mouse Egfl7 expressed at embryonic day 7.5 exclusively in the primitive blood islands where the first endothelial cells differentiate, and later in endothelial cells of a wide range of tissues. Fluorescence-labeled Egfl7 was expressed in the endoplasmic reticulum of transfected mouse fibroblasts, and it was secreted into the culture medium.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Hu01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Hu01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Hu01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Hu01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Hu01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Mu01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Mu01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Mu01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Mu01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Mu01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Ra01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Ra01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Ra01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Ra01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Ra01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Ca01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Ca01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Ca01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Ca01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Ca01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Po01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Po01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Po01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Po01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Po01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Bo01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Bo01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Bo01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Bo01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Bo01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Rb01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Rb01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Rb01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Rb01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Rb01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM923Mo01 | Recombinant EGF Like Domain Protein, Multiple 7 (EGFL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM923Mo01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IP. |
| PAM923Mo01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM923Mo01 | CLIA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | CLIA assay for Antigen Detection |
| ELM923Mo01 | ELISA Kit for EGF Like Domain Protein, Multiple 7 (EGFL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"EGFL7 ligates alphavbeta3 integrin to enhance vessel formation."
Blood 121:3041-3050(2013) [PubMed] [Europe PMC] [Abstract]
"CASZ1 promotes vascular assembly and morphogenesis through the direct regulation of an EGFL7/RhoA-mediated pathway."
Dev. Cell 25:132-143(2013) [PubMed] [Europe PMC] [Abstract]