Family With Sequence Similarity 3, Member C (FAM3C)
ILEI; Predicted Osteoblast Protein; Interleukin Like EMT Inducer
This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. Alternate transcriptional splice variants which encode the same protein have been characterized.
By searching a database for sequences similar to FAM3A, followed by RT-PCR of heart mRNA, Zhu et al. (2002) cloned FAM3C. The deduced 227-amino acid protein contains an N-terminal signal peptide. The authors predicted that FAM3C forms a 4-helix bundle, and 3-dimensional modeling indicated that 4 cysteines could form 2 disulfide bonds linking helices 1 and 4 and helices 2 and 3. Northern blot analysis detected FAM3C expression in almost all tissues tested.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Hu01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Hu01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Hu01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Hu01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Hu01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Mu01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Mu01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Mu01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Mu01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Mu01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Ra01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Ra01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Ra01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Ra01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Ra01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Ca01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Ca01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Ca01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Ca01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Ca01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Po01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Po01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Po01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Po01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Po01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Bo01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Bo01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Bo01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Bo01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Bo01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Rb01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Rb01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Rb01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Rb01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Rb01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM877Mo01 | Recombinant Family With Sequence Similarity 3, Member C (FAM3C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM877Mo01 | Monoclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IP. |
| PAM877Mo01 | Polyclonal Antibody to Family With Sequence Similarity 3, Member C (FAM3C) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM877Mo01 | CLIA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | CLIA assay for Antigen Detection |
| ELM877Mo01 | ELISA Kit for Family With Sequence Similarity 3, Member C (FAM3C) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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"ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression."
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