Myxovirus Resistance 1 (MX1)
IFI-78K; IFI78; MX; MxA; Interferon-Inducible Protein p78; Interferon-regulated resistance GTP-binding protein MxA
MxA is a downstream target of FAC and is the first genetic marker to be identified among multiple FA complementation groups. FA subtypes may converge onto a final common pathway, which is intimately related to the interferon signaling mechanism. Constitutive activity of this pathway may explain a number of the phenotypic features of FA, particularly the pathogenesis of bone marrow failure.In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Hu01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Hu01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Hu01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Hu01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Hu01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Mu01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Mu01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Mu01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Mu01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Mu01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Ra01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Ra01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Ra01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Ra01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Ra01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Ca01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Ca01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Ca01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Ca01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Ca01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Po01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Po01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Po01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Po01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Po01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Bo01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Bo01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Bo01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Bo01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Bo01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Rb01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Rb01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Rb01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Rb01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Rb01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPM630Mo01 | Recombinant Myxovirus Resistance 1 (MX1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAM630Mo01 | Monoclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IP. |
| PAM630Mo01 | Polyclonal Antibody to Myxovirus Resistance 1 (MX1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLM630Mo01 | CLIA Kit for Myxovirus Resistance 1 (MX1) | CLIA assay for Antigen Detection |
| ELM630Mo01 | ELISA Kit for Myxovirus Resistance 1 (MX1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"cDNA structures and regulation of two interferon-induced human Mx proteins."
Mol. Cell. Biol. 9:5062-5072(1989) [PubMed] [Europe PMC] [Abstract]
"Cloning and sequence analyses of cDNAs for interferon- and virus-induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter."
J. Virol. 64:1171-1181(1990) [PubMed] [Europe PMC] [Abstract]
"Structure and polymorphism of the human gene for the interferon-induced p78 protein (MX1): evidence of association with alopecia areata in the Down syndrome region."
Hum. Genet. 106:639-645(2000) [PubMed] [Europe PMC] [Abstract]
"Herpes simplex virus-1 induces expression of a novel MxA isoform that enhances viral replication."
Immunol. Cell Biol. 89:173-182(2011) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 21."
Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]