Epigen (EPG)

EPGN; Epithelial Mitogen Homolog

SPN	L110
HGNC	17470
MGI	1919170
PubMed	23996651
RGD	1560084
UniProt	Q6UW88
Wiki	Epigen

Epogen is a prescription drug that is used to treat anemia due to chemotherapy, chronic kidney failure, and zidovudine (an HIV medication). Taking the medicine before surgery can also decrease the need for blood transfusions in people with anemia.

Epogen can be given either by IV or as an injection under the skin. It is generally given once a week or three times a week, depending on certain factors. Side effects may include constipation, nausea, fever, and fatigue. During treatment, it is important that your body has enough iron, otherwise Epogen cannot work well. Your healthcare provider may recommend iron supplements if necessary.

Reference

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity."
J. Biol. Chem. 280:8503-8512(2005) [PubMed] [Europe PMC] [Abstract]