EGF Like Domain Protein, Multiple 6 (EGFL6)
MAEG; MAM And EGF Domain Containing; Epidermal growth factor-like protein 6
EGFL6 encodes a member of the epidermal growth factor (EGF) repeat superfamily.The predicted 553-amino acid EGFL6 protein has a putative N-terminal signal peptide, which suggests that it is secreted; an EGF repeat region containing 4 complete EGF-like repeats and 1 partial EGF-like repeat; an integrin association motif (RGD); 2 potential N-glycosylation sites; and a potential tyrosine phosphorylation site. Northern blot analysis of a variety of normal human tissues detected an approximately 2.4-kb EGFL6 transcript only in placenta. Among the cancer tissues tested, EGFL6 expression was found only in meningioma tumors. Screening-by-hybridization analysis of various cDNA libraries indicated EGFL6 expression in lung tumor, fetal lung, fetal skin, fetal umbilical cord, fetal liver/spleen, and placenta, but not in normal adult tissues, including lung.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Hu01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Hu01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Hu01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Hu01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Hu01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Mu01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Mu01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Mu01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Mu01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Mu01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Ra01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Ra01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Ra01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Ra01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Ra01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Ca01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Ca01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Ca01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Ca01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Ca01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Po01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Po01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Po01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Po01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Po01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Bo01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Bo01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Bo01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Bo01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Bo01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Rb01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Rb01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Rb01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Rb01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Rb01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ666Mo01 | Recombinant EGF Like Domain Protein, Multiple 6 (EGFL6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ666Mo01 | Monoclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IP. |
| PAJ666Mo01 | Polyclonal Antibody to EGF Like Domain Protein, Multiple 6 (EGFL6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ666Mo01 | CLIA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | CLIA assay for Antigen Detection |
| ELJ666Mo01 | ELISA Kit for EGF Like Domain Protein, Multiple 6 (EGFL6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Cloning of a novel epidermal growth factor repeat containing gene EGFL6: expressed in tumor and fetal tissues."
Genomics 62:304-307(1999) [PubMed] [Europe PMC] [Abstract]
"Identification of a new EGF-repeat-containing gene from human Xp22: a candidate for developmental disorders."
Genomics 65:16-23(2000) [PubMed] [Europe PMC] [Abstract]
"Large-scale cDNA transfection screening for genes related to cancer development and progression."
Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]