Glutamate Decarboxylase Like Protein 1 (GADL1)
ADC; CSADC; Acidic amino acid decarboxylase GADL1; Aspartate 1-decarboxylase; Cysteine sulfinic acid decarboxylase
GADL1, Belongs to the group II decarboxylase family. Glutamate decarboxylase or glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses PLP as a cofactor.
In mammals, GAD exists in two isoforms encoded by two different genes - Gad1 and Gad2. These isoforms are GAD67 and GAD65 with molecular weights of 67 and 65 kDa, respectively. GAD1 and GAD2 are expressed in the brain where GABA is used as a neurotransmitter, GAD2 is also expressed in the pancreas.
At least two more forms, GAD25 and GAD44 (embryonic; EGAD) are described in the developing brain. They are coded by the alternative transcripts of GAD1, I-80 and I-86: GAD25 is coded by both, GAD44 - only by I-80.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Hu01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Hu01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Hu01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Hu01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Hu01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Mu01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Mu01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Mu01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Mu01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Mu01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Ra01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Ra01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Ra01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Ra01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Ra01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Ca01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Ca01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Ca01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Ca01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Ca01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Po01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Po01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Po01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Po01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Po01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Bo01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Bo01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Bo01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Bo01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Bo01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Rb01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Rb01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Rb01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Rb01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Rb01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPJ389Mo01 | Recombinant Glutamate Decarboxylase Like Protein 1 (GADL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAJ389Mo01 | Monoclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IP. |
| PAJ389Mo01 | Polyclonal Antibody to Glutamate Decarboxylase Like Protein 1 (GADL1) | WB; IHC; ICC; IF. | |
| Assay Kits | CLJ389Mo01 | CLIA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | CLIA assay for Antigen Detection |
| ELJ389Mo01 | ELISA Kit for Glutamate Decarboxylase Like Protein 1 (GADL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Role of glutamate decarboxylase-like protein 1 (GADL1) in taurine biosynthesis."
J. Biol. Chem. 287:40898-40906(2012) [PubMed] [Europe PMC] [Abstract]