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Neugrin (NGRN)

Neurite Outgrowth Associated; Mesenchymal stem cell protein DSC92; Spinal cord-derived protein FI58G

The neugrin mRNA encodes 219 amino acids and its deduced amino acid sequence contains an NLS-like domain. No previously known motif is found in it. m-neugrin mRNA encodes 233 amino acids. Neugrin and m-Neugrin are 70% homologous in amino acid sequence. Northern analysis revealed that neugrin was strongly expressed in the heart, brain, and skeletal muscle, and m-neugrin in the liver, kidney, and brain. A transfection study indicated that these proteins are localized in the nucleus. Although the expression of neugrin was found to be ubiquitous in the nervous system, in situ hybridization showed that both neugrin and m-neugrin were expressed mainly in the neurons rather than the glial cells. Their expression was highly upregulated with the neurite outgrowth associated with neuronal differentiation in neuroblastoma cell lines.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Hu01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Hu01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Hu01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Hu01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Hu01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Mu01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Mu01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Mu01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Mu01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Mu01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Ra01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Ra01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Ra01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Ra01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Ra01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Ca01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Ca01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Ca01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Ca01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Ca01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Po01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Po01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Po01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Po01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Po01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Bo01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Bo01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Bo01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Bo01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Bo01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Rb01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Rb01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Rb01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Rb01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Rb01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPI934Mo01 Recombinant Neugrin (NGRN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAI934Mo01 Monoclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IP.
PAI934Mo01 Polyclonal Antibody to Neugrin (NGRN) WB; IHC; ICC; IF.
Assay Kits CLI934Mo01 CLIA Kit for Neugrin (NGRN) CLIA assay for Antigen Detection
ELI934Mo01 ELISA Kit for Neugrin (NGRN) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Two novel genes, human neugrin and mouse m-neugrin, are upregulated with neuronal differentiation in neuroblastoma cells."
Biochem. Biophys. Res. Commun. 279:526-533(2000) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"Analysis of the DNA sequence and duplication history of human chromosome 15."
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning."
Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]