Angiopoietin Like Protein 7 (ANGPTL7)
CDT6; AngX; Cornea-Derived Transcript 6; Angiopoietin-related protein 7; Angiopoietin-like factor
CDT6 is a member of the angiopoietin gene family. CDT6 is a secreted protein that folds into disulfide-linked homotetramers by coiled-coil interactions. The finding that CDT6 is expressed at high levels in the avascular corneal stromal layer suggested that the protein, similar to certain angiopoietins, acts as a negative regulator of angiogenesis. To test this hypothesis and to assay the effect of the protein on a growing tissue with high vascular density, CDT6 was expressed in a mouse xenograft model. Expression of CDT6 led to a reduction in tumor growth and aberrant blood vessel formation by inducing massive fibrosis. Interestingly, expression of CDT6 also resulted in the deposition of extracellular matrix components typical for the mature corneal stromal layer.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Hu01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Hu01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Hu01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Hu01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Hu01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Mu01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Mu01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Mu01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Mu01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Mu01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Ra01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Ra01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Ra01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Ra01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Ra01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Ca01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Ca01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Ca01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Ca01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Ca01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Po01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Po01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Po01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Po01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Po01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Bo01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Bo01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Bo01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Bo01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Bo01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Rb01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Rb01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Rb01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Rb01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Rb01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPH875Mo01 | Recombinant Angiopoietin Like Protein 7 (ANGPTL7) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAH875Mo01 | Monoclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IP. |
| PAH875Mo01 | Polyclonal Antibody to Angiopoietin Like Protein 7 (ANGPTL7) | WB; IHC; ICC; IF. | |
| Assay Kits | CLH875Mo01 | CLIA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | CLIA assay for Antigen Detection |
| ELH875Mo01 | ELISA Kit for Angiopoietin Like Protein 7 (ANGPTL7) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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