Solute Carrier Family 30, Member 10 (SLC30A10)
ZnT-10; ZRC1; ZNT8; Zinc Transporter 8
Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A10, permit cellular efflux of zinc.
By searching databases with ZNT sequences, Seve et al. (2004) identified SLC30A10, which they called ZNT10. The deduced protein has a calculated molecular mass of 52.7 kD. It has 6 transmembrane helices, a basic region between helices 4 and 5, and cytoplasmic N and C termini. EST database analysis showed evidence of SLC30A10 expression only in fetal brain and fetal liver.Seve et al. (2004) determined that the SLC30A10 gene contains 4 exons and spans 15 kb.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Hu01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Hu01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Hu01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Hu01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Hu01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Mu01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Mu01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Mu01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Mu01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Mu01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Ra01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Ra01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Ra01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Ra01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Ra01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Ca01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Ca01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Ca01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Ca01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Ca01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Po01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Po01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Po01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Po01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Po01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Bo01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Bo01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Bo01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Bo01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Bo01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Rb01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Rb01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Rb01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Rb01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Rb01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPG375Mo01 | Recombinant Solute Carrier Family 30, Member 10 (SLC30A10) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAG375Mo01 | Monoclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IP. |
| PAG375Mo01 | Polyclonal Antibody to Solute Carrier Family 30, Member 10 (SLC30A10) | WB; IHC; ICC; IF. | |
| Assay Kits | CLG375Mo01 | CLIA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | CLIA assay for Antigen Detection |
| ELG375Mo01 | ELISA Kit for Solute Carrier Family 30, Member 10 (SLC30A10) | Enzyme-linked immunosorbent assay for Antigen Detection |
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BMC Genomics 5:32-32(2004) [PubMed] [Europe PMC] [Abstract]
"Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man."
Am. J. Hum. Genet. 90:457-466(2012) [PubMed] [Europe PMC] [Abstract]
"Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease."
Am. J. Hum. Genet. 90:467-477(2012) [PubMed] [Europe PMC] [Abstract]