Call Now

Myelin Proteolipid Protein Like Protein (PLPL)

C14orf162; CCDC177; Coiled-coil domain-containing protein 177

Myelin proteolipid protein (PLP or lipophilin) is the major myelin protein from the central nervous system (CNS). It plays an important role in the formation or maintenance of the multilamellar structure of myelin. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction.In man point mutations in PLP are the cause of Pelizaeus-Merzbacher disease (PMD), a neurologic disorder of myelin metabolism. In animals dismyelinating diseases such as mouse 'jimpy' or dog 'shaking pup' are also caused by mutations in PLP.PLP is a highly conserved hydrophobic protein of 276 to 280 amino acids which seems to contain four transmembrane segments, two disulfide bonds and which covalently binds lipids (at least six palmitate groups in mammals). PLP is highly related to GPM6A, a neuronal membrane glycoprotein.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Hu01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Hu01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Hu01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Hu01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Hu01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Mu01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Mu01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Mu01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Mu01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Mu01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Ra01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Ra01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Ra01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Ra01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Ra01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Ca01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Ca01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Ca01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Ca01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Ca01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Po01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Po01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Po01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Po01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Po01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Bo01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Bo01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Bo01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Bo01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Bo01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Rb01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Rb01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Rb01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Rb01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Rb01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD067Mo01 Recombinant Myelin Proteolipid Protein Like Protein (PLPL) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAD067Mo01 Monoclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IP.
PAD067Mo01 Polyclonal Antibody to Myelin Proteolipid Protein Like Protein (PLPL) WB; IHC; ICC; IF.
Assay Kits CLD067Mo01 CLIA Kit for Myelin Proteolipid Protein Like Protein (PLPL) CLIA assay for Antigen Detection
ELD067Mo01 ELISA Kit for Myelin Proteolipid Protein Like Protein (PLPL) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 14."
Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]