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Interferon Tau (IFNt)

IFN-T1; TP1; OTP; Trophoblastin; Interferon Tau-1; Trophoblast Protein 1; Trophoblast Antiluteolytic Protein; Antiluteolysin

Interferon tau is a Type I interferon made up of a single chain of amino-acids. In many species of ruminant, it acts as a signaling molecule during pregnancy. It is secreted by the trophoblast cells into the uterine lumen in days 13-21 of pregnancy. It decreases endometrial oxytocin receptors, which then cannot stimulate PGF-2-alpha synthesis, preventing luteolysis. It promotes uterine implantation by increasing protein synthesis in glands. Although its role in humans is not certain, it has been found to bind to the same receptors sensitive to interferon alpha, and thus may have anti-viral properties, as hinted by studies showing its ability to inhibit the reverse transcriptase enzyme found in retroviruses such as HIV. Its low toxicity compared to other interferons also supports its investigation as a potential therapeutic compound.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins A908Bo01 Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits KEA908Bo ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interferon Tau (IFNt) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interferon Tau (IFNt) Bioactivity
Antibodies NONE Monoclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interferon Tau (IFNt) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interferon Tau (IFNt) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interferon Tau (IFNt) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interferon Tau (IFNt) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interferon Tau (IFNt) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interferon Tau (IFNt) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interferon Tau (IFNt) CLIA assay for Antigen Detection

Reference

"Interferon-like sequence of ovine trophoblast protein secreted by embryonic trophectoderm."
Nature 330:377-379(1987) [PubMed] [Europe PMC] [Abstract]

"Ovine interferon tau suppresses transcription of the estrogen receptor and oxytocin receptor genes in the ovine endometrium."
Endocrinology 137:1144-1147(1996) [PubMed] [Europe PMC] [Abstract]

"Predicted structural motif of IFN tau."
Protein Eng. 7:863-867(1994) [PubMed] [Europe PMC] [Abstract]

"A three-dimensional model of interferon-tau."
J. Interferon Cytokine Res. 15:1053-1060(1995) [PubMed] [Europe PMC] [Abstract]

"IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities."
Biochimie 80:755-777(1998) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of ovine interferon-tau at 2.1 A resolution."
J. Mol. Biol. 286:151-162(1999) [PubMed] [Europe PMC] [Abstract]