Erectile Dysfunction (ED)
Erectile dysfunction (ED) or impotence is sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity in humans. A penile erection is the hydraulic effect of blood entering and being retained in sponge-like bodies within the penis. The process is most often initiated as a result of sexual arousal, when signals are transmitted from the brain to nerves in the penis. The most important organic causes of impotence are cardiovascular disease and diabetes, neurological problems , hormonal insufficiencies and drug side effects.
Researchers developed a model of traumatic arteriogenic (ED) for the study of vasculogenic ED. Bilateral ligation of the internal iliac artery was performed on 30 three-month old male as an experimental group. Further studies are needed to investigate the molecular mechanism of ED in this model.