Sjogren Syndrome (SS)
Sjögren's syndrome; SjS
Sjögren's syndrome(Sjogren's syndrome) is an autoimmune disease with clinical hallmarks of keratoconjunctivitis sicca and xerostomia. Other symptoms can include dry skin, a chronic cough, vaginal dryness, numbness in the arms and legs, feeling tired, muscle and joint pains, and thyroid problems. Those affected are at an increased risk of lymphoma.
The exact cause is unclear, but it is believed to involve a combination of genetics and an environmental trigger such as exposure to a virus or bacteria. It can occur independently of other health problems (primary Sjögren's syndrome) or as a result of another connective tissue disorder (secondary Sjögren's syndrome). The inflammation that results progressively damages the glands.