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Kaschin-Beck Disease (KBD)

Kashin–Beck disease (KBD) is a chronic, endemic type of osteochondropathy. KBD usually involves children ages 5–15. To date, more than a million individuals have suffered from KBD. The symptoms of KBD include joint pain, morning stiffness in the joints, disturbances of flexion and extension in the elbows, enlarged inter-phalangeal joints and limited motion in many joints of the body. Death of cartilage cells in the growth plate and articular surface is the basic pathologic feature; this can result in growth retardation and secondary osteoarthrosis. A model for rat Kashin-Beck disease induced by employing T-2 toxin treatment under selenium deficient conditions was established by researchers. Studies showed that increasing TBARS and decreasing antioxidants in serum and cartilage by T-2 toxin treatment with a selenium-deficient nutritional status may alter oxidative stress in joint tissues and contribute to the pathological process of cartilage damage in KBD.

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins N/A Recombinant Kaschin-Beck Disease (KBD) Antigenic Transformation Customized Service Offer
Antibodies N/A Monoclonal Antibody to Kaschin-Beck Disease (KBD) Monoclonal Antibody Customized Service Offer
N/A Polyclonal Antibody to Kaschin-Beck Disease (KBD) Polyclonal Antibody Customized Service Offer
Assay Kits N/A CLIA Kit for Kaschin-Beck Disease (KBD) CLIA Kit Customized Service Offer
N/A ELISA Kit for Kaschin-Beck Disease (KBD) ELISA Kit Customized Service Offer