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Duodenal Ulcer (DU)

A duodenal ulcer is usually caused by an infection with a germ (bacterium) called Helicobacter pylori (H. pylori). A 4- to 8-week course of acid-suppressing medication will allow the ulcer to heal. In addition, a one-week course of two antibiotics plus an acid-suppressing medicine will usually clear the H. pylori infection. This usually prevents the ulcer from coming back. Anti-inflammatory medicines used to treat conditions such as arthritis sometimes cause duodenal ulcers. If you need to continue with the anti-inflammatory medicine then you may need to take long-term acid-suppressing medication.