Pancreatic Microcirculatory Failure (PMF)
Pancreatic Microcirculatory Disturbance; Pancreatic microcirculatory impairment
Neutrophil-mediated tissue injury in acute pancreatitis includes a severe reduction of the functional microcirculation via interaction of adhesion molecules on leukocytes (MAC-1) and endothelium (ICAM-1). The hypothesis of the study was that trypsin and elastase in serum alone lead to the expression of these complementary adhesion molecules and result in increased leukocyte-endothelial interaction (LEI). In addition we evaluated the preventative benefit of protease inhibition on these mechanisms. These results support the role of circulating trypsin and elastase in promoting pancreatic microcirculatory failure in experimental acute pancreatitis.
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | N/A | Recombinant Pancreatic Microcirculatory Failure (PMF) | Antigenic Transformation Customized Service Offer |
| Antibodies | N/A | Monoclonal Antibody to Pancreatic Microcirculatory Failure (PMF) | Monoclonal Antibody Customized Service Offer |
| N/A | Polyclonal Antibody to Pancreatic Microcirculatory Failure (PMF) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | N/A | CLIA Kit for Pancreatic Microcirculatory Failure (PMF) | CLIA Kit Customized Service Offer |
| N/A | ELISA Kit for Pancreatic Microcirculatory Failure (PMF) | ELISA Kit Customized Service Offer |