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Dental Fluorosis (DF)

Fluorosis teeth; Mottled enamel

Dental fluorosis is an extremely common disorder, characterized by hypomineralization of tooth enamel caused by ingestion of excessive fluoride during enamel formation. It appears as a range of visual changes in enamel causing degrees of intrinsic tooth discoloration, and, in some cases, physical damage to the teeth. The severity of the condition is dependent on the dose, duration and age of the individual during the exposure. 

Examination of inbred strains of mice showed differences in dental fluorosis susceptibility/resistance. The A/J mouse strain is highly susceptible, with a rapid onset and severe development of dental fluorosis compared with that in the other strains tested, whereas the 129P3/J mouse strain is least affected, with minimal dental fluorosis. These observations support the contribution of a genetic component in the pathogenesis of dental fluorosis.

Organism species: Pan-species (General)

Proteins N/A Recombinant Dental Fluorosis (DF) Antigenic Transformation Customized Service Offer
Antibodies N/A Monoclonal Antibody to Dental Fluorosis (DF) Monoclonal Antibody Customized Service Offer
N/A Polyclonal Antibody to Dental Fluorosis (DF) Polyclonal Antibody Customized Service Offer
Assay Kits N/A CLIA Kit for Dental Fluorosis (DF) CLIA Kit Customized Service Offer
N/A ELISA Kit for Dental Fluorosis (DF) ELISA Kit Customized Service Offer