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Corneal Endothelial Injury (CEI)

Although leukocyte-mediated cell injury has long been suggested as a major mechanism of general tissue injury in acute and chronic inflammation, only limited data have been developed to directly implicate leukocytes in ocular tissue injury. In an effort to unravel the role and mechanisms of leukocyte-mediated injury to the cornea, an isolated corneal cup model was developed. For this model, peripheral bovine leukocytes were added to isolated bovine corneal cultures (corneal cup) in vitro, after which endothelial cell damage and death were evaluated morphologically. In general, corneal endothelial cell swelling was observed within 5-10 minutes after leukocyte exposure, followed by detachment of the corneal endothelium at a 30-75-minute interval.

Organism species: Pan-species (General)

Proteins N/A Recombinant Corneal Endothelial Injury (CEI) Antigenic Transformation Customized Service Offer
Antibodies N/A Monoclonal Antibody to Corneal Endothelial Injury (CEI) Monoclonal Antibody Customized Service Offer
N/A Polyclonal Antibody to Corneal Endothelial Injury (CEI) Polyclonal Antibody Customized Service Offer
Assay Kits N/A CLIA Kit for Corneal Endothelial Injury (CEI) CLIA Kit Customized Service Offer
N/A ELISA Kit for Corneal Endothelial Injury (CEI) ELISA Kit Customized Service Offer