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Allergic Encephalomyelitis (AE)

The experimental autoimmune encephalomyelitis, sometimes experimental allergic encephalomyelitis (EAE) is an animal model of brain inflammation. It is an inflammatory demyelinating disease of the central nervous system (CNS). It is mostly used with rodents and is widely studied as an animal model of the human CNS demyelinating diseases, including multiple sclerosis and acute disseminated encephalomyelitis (ADEM). EAE is also the prototype for T-cell-mediated autoimmune disease in general. EAE can be induced in a number of species, including mice, rats, guinea pigs, rabbits and primates. The most commonly used antigens in rodents are spinal cord homogenate (SCH), purified myelin, myelin protein such as MBP, PLP and MOG, or peptides of these proteins, all resulting in distinct models with different disease characteristics regarding both immunology and pathology.

Organism species: Pan-species (General)

Proteins N/A Recombinant Allergic Encephalomyelitis (AE) Antigenic Transformation Customized Service Offer
Antibodies N/A Monoclonal Antibody to Allergic Encephalomyelitis (AE) Monoclonal Antibody Customized Service Offer
N/A Polyclonal Antibody to Allergic Encephalomyelitis (AE) Polyclonal Antibody Customized Service Offer
Assay Kits N/A CLIA Kit for Allergic Encephalomyelitis (AE) CLIA Kit Customized Service Offer
N/A ELISA Kit for Allergic Encephalomyelitis (AE) ELISA Kit Customized Service Offer