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Imperforate Anus (IA)

ARMs; Anorectal malformations

An imperforate anus are birth defects in which the rectum is malformed. ARMs are a spectrum of different congenital anomalies in males and females, that varies from fairly minor lesions to complex anomalies. The cause of ARMs is unknown; the genetic basis of these anomalies is very complex because of their anatomical variability. In 8% of patients genetic factors are clearly associated with ARMs. Anorectal malformation in Currarino syndrome represents the only association for which the gene HLXB9 has been identified. Imperforate anus usually requires immediate surgery to open a passage for feces unless a fistula can be relied on until corrective surgery takes place. Depending on the severity of the imperforate, it is treated either with a perineal anoplasty or with a colostomy.

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins N/A Recombinant Imperforate Anus (IA) Antigenic Transformation Customized Service Offer
Antibodies N/A Monoclonal Antibody to Imperforate Anus (IA) Monoclonal Antibody Customized Service Offer
N/A Polyclonal Antibody to Imperforate Anus (IA) Polyclonal Antibody Customized Service Offer
Assay Kits N/A CLIA Kit for Imperforate Anus (IA) CLIA Kit Customized Service Offer
N/A ELISA Kit for Imperforate Anus (IA) ELISA Kit Customized Service Offer